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Carbon nanospheres almost double rat lifespan:...

by AgeVivo and Sven Bulterijs more discussion of the paper in question in this thread in the C60 Health sub-forum this article is a work in progress, it may change over time based on discussions and...

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crowdsourced multivitamin

Extending maximum human lifespan will likely require a wide range of new biotechnology. Powerful interventions such as pharmaceuticals, stem cell technology, and gene therapy are in development but...

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"Healthy Aging" is not enough

A Response to the "Compression of Morbidity" Mindset "...there is no basis for the ardent hopes and positive statements made as to [its] safety and success[..], and [..] therefore, it would be a...

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Honorary Member: Fred Chamberlain (boundlesslife)

View attachment: fred.jpgIn the early 1970's Fred Chamberlain, together with his wife Linda founded the cryonics corporations Manrise and the Alcor Society for Solid State Hypothermia, The latter...

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Assessing the effects of c60 on human cancer pr...

 View attachment: c60re02.png  "Assessing the effects of c60 on human cancer proliferation in vivo"is led by life-extension trailblazer Kelsey Moody. It is interesting that he turns the attention of...

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Supplement Review: Nicotinamide Riboside

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Article: Gut microbiome in health and aging

As part of his new column "Sven's Science Corner" Sven Bulterijs discusses novel insights into the crucial role gut bacteria seem to play in health, disease and aging. ⇒ read the article in "Sven's...

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Why do some turtles outlive humans?

(⇒ write for LongeCity ) The oldest human recorded in modernity was Jeanne Louise Calment, she died in the age of 122 years and 164 days [1] . There are rumors that the oldest tortoise called Adwaita...

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Aschwin de Wolf: Cryonics

Interview with Aschwin de Wolf (February, 2017) Aschwin de Wolf    is the CEO of Advanced Neural Biosciences, a neural cryobiology research company in Portland, Oregon. Originally from the Netherlands,...

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Metformin - a geroprotector?

Sven Bulterijs first discussed the potential utility of anti-diabetic substance metformin six years ago on LongeCity. Now Sven returns to the topic with a comprehensive and thoughtful discussion of the...

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Geroprotector Review: Rapamycin and other mTOR...

Sven Bulterijs continues his discussion of prominent compounds with potential life extension efficacy by looking not just at rapamycin but also at its target, the mTOR pathway, which has likely a key...

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Aging theories: Is there a unifying factor in a...

When Darwin’s theory of evolution by natural selection was established, biologists were puzzled by the existence of senescence and aging among all organisms. Why did the evolutionary pressure not...

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Nootropics in human trials (Intro)

The word "nootropic" derives from the Greek words nous, or "mind", and trepein meaning "to bend or turn". It was first coined by Romanian psychologist and chemist, Corneliu E. Giurgea after...

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Antioxidants- relevant for life extension?

Harman published his free radical theory of aging in 1956 and in the following decades it slowly became probably the most popular explanation of the mechanism of aging (Ashok & Ali, 1999). Because...

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Aging Theories: is an 'aging program' a...

The big and continuing mystery about aging has been as described by Vit Zemanek in his recent Longecity article [1] “When Darwin’s theory of evolution by natural selection was established, biologists...

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Cryonics

The following is a quick overview on Cryonics. NB: The information below is periodically reviewed for accuracy, but LongeCity makes no representations or gives any warranties whatsoever that the...

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8 Reasons to reach out to 'the public'

While the idea that drastic life extension may be an option for humankind in the future has been encountered by many through the media and fiction, the vast majority of the public do not grasp whether...

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Pioneers: Marquis de Condorcet (1743-1794)

The 18th-century Age of Enlightenment brought forth a paradigm shift in perceptions of the human condition and potential. The thinkers of the Enlightenment systematically articulated the case for...

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Eternus by Neurohacker Collective

SPONSORRED GUEST ARTICLE Eternus Science Neurohacker Collective put rigorous research into the formulation of their Qualia nootropic stack products which debuted in 2016. They now have turned their...

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'Nugenics' - breakthrough rejuvenation?

On May 7, a study was posted on bioRxiv that has all the apprearance of a potential major breakthrough in anti-aging research. The researchers claim they've made a mammal 54% younger with a few simple...

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